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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN3
All Species:
19.7
Human Site:
S165
Identified Species:
30.95
UniProt:
Q6P5Z2
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P5Z2
NP_037487.2
889
99421
S165
L
L
R
M
K
I
S
S
L
E
A
S
G
S
P
Chimpanzee
Pan troglodytes
XP_001159776
886
99121
S165
L
L
R
M
K
I
S
S
L
E
A
S
G
S
P
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
S278
L
L
R
M
K
I
S
S
L
E
A
S
G
S
P
Dog
Lupus familis
XP_548434
951
104664
S227
L
L
R
M
K
I
S
S
L
E
A
S
G
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8K045
878
97863
S158
L
L
R
M
K
I
S
S
L
E
S
S
G
S
P
Rat
Rattus norvegicus
O08874
985
112050
Q197
V
I
R
M
H
I
L
Q
A
V
L
T
N
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
K265
L
L
R
M
Q
I
G
K
L
G
A
G
E
A
T
Chicken
Gallus gallus
XP_422357
1013
114806
Q223
V
I
R
M
Q
I
L
Q
A
V
Q
T
N
E
L
Frog
Xenopus laevis
Q7ZX15
486
56292
Zebra Danio
Brachydanio rerio
XP_697542
940
106140
K179
L
L
R
M
Q
I
V
K
V
T
Q
A
R
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
E51
A
V
N
K
E
F
K
E
R
A
G
F
N
R
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
S108
F
D
Q
L
K
I
G
S
A
N
D
I
W
V
D
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
V103
A
E
A
Q
K
G
L
V
E
A
S
H
K
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
D149
K
L
Y
Q
I
D
G
D
Q
R
S
S
S
A
A
Red Bread Mold
Neurospora crassa
P87253
1142
127954
D146
R
P
N
Y
T
R
L
D
L
I
K
F
D
T
P
Conservation
Percent
Protein Identity:
100
97.7
81.5
84.2
N.A.
83.2
49.9
N.A.
64.2
48.9
26.2
52.2
N.A.
28
N.A.
29.1
41.5
Protein Similarity:
100
97.8
82.9
87.6
N.A.
88.4
63.6
N.A.
72.9
63
36.6
67.6
N.A.
41.5
N.A.
43.9
58.2
P-Site Identity:
100
100
100
100
N.A.
93.3
20
N.A.
46.6
20
0
33.3
N.A.
0
N.A.
20
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
40
N.A.
60
46.6
0
53.3
N.A.
13.3
N.A.
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
27.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.7
43.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
7
0
0
0
0
0
20
14
34
7
0
14
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
7
0
14
0
0
7
0
7
0
14
% D
% Glu:
0
7
0
0
7
0
0
7
7
34
0
0
7
20
0
% E
% Phe:
7
0
0
0
0
7
0
0
0
0
0
14
0
0
0
% F
% Gly:
0
0
0
0
0
7
20
0
0
7
7
7
34
0
7
% G
% His:
0
0
0
0
7
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
14
0
0
7
67
0
0
0
7
0
7
0
0
0
% I
% Lys:
7
0
0
7
47
0
7
14
0
0
7
0
7
0
0
% K
% Leu:
47
54
0
7
0
0
27
0
47
0
7
0
0
7
14
% L
% Met:
0
0
0
60
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
14
0
0
0
0
0
0
7
0
0
20
0
0
% N
% Pro:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
40
% P
% Gln:
0
0
7
14
20
0
0
14
7
0
14
0
0
0
0
% Q
% Arg:
7
0
60
0
0
7
0
0
7
7
0
0
7
7
7
% R
% Ser:
0
0
0
0
0
0
34
40
0
0
20
40
7
34
0
% S
% Thr:
0
0
0
0
7
0
0
0
0
7
0
14
0
7
7
% T
% Val:
14
7
0
0
0
0
7
7
7
14
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
7
7
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _